Mediterranean Diet Cognitive Function and Dementia a Systematic Review

Review

. 2016 Sep fifteen;seven(5):889-904.

doi: 10.3945/an.116.012138. Print 2016 Sep.

Mediterranean Diet, Cerebral Function, and Dementia: A Systematic Review of the Evidence

Affiliations

• PMID: 27633105
• PMCID: PMC5015034
• DOI: x.3945/an.116.012138

Free PMC article

Review

Mediterranean Diet, Cerebral Function, and Dementia: A Systematic Review of the Evidence

Sara Danuta Petersson  et al. Adv Nutr. 2016 .

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Abstract

A growing torso of evidence suggests that adherence to the Mediterranean nutrition (Doctor) may protect confronting cognitive decline and dementia. Many epidemiologic studies and several randomized controlled trials (RCTs) have found positive effects of the MD on cognitive role, only findings remain inconsistent. The aim of this systematic review was to provide an update on the current knowledge of the effects of the MD on cerebral part, cognitive impairment, Alzheimer affliction (Advert), and all-blazon dementia. Five databases were searched-PubMed, Embase, CINAHL, Key, and PsycINFO (1806 to 25 May 2015)-with the utilize of prespecified criteria. Human being studies that were published in English without any brake on study blazon, population assessed, intervention period, follow-upwards time, or publication appointment, and that examined the association between adherence to the MD and cognitive office or dementia symptoms (as measured by cognitive function tests), were included. Only master publication types were included. Xxx-2 studies from 25 unique cohorts, including 5 RCTs and 27 observational studies, met the inclusion criteria. The majority of studies showed that the Medico was associated with improved cognitive office, a decreased risk of cerebral damage or decreased risk of dementia, or Advertising. Three studies establish no correlation between the Doctor and AD, 3 farther studies plant no clan between the Doc and cerebral impairment, and 5 studies found no clan between the MD and cognitive role. There was big heterogeneity, and studies differed with regard to quality. Based on the findings and the limitations in written report design, we conclude that adherence to the MD is associated with meliorate cognitive performance. However, it should be noted that the majority of findings come from epidemiologic studies that provide bear witness for a correlation between the MD and knowledge but not for a cause-and-effect relation. More than controlled trials are required to establish a causational relation.

Keywords: Alzheimer disease; Mediterranean nutrition; cognitive function; cognitive impairment; dementia; dietary patterns; systematic review.

© 2016 American Lodge for Nutrition.

Conflict of involvement argument

2 Author disclosures: SD Petersson and Eastward Philippou, no conflicts of interest.

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Flowchart of the report choice process.

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